Mycobacterium phlei as an oral immunomodulator with Newcastle disease vaccine.

Effect of Levamisole as an Immunomodulator in Cockerels Vaccinated with Newcastle Disease Vaccine

The efficacy of Levamisole Hydrochloride-a standard immunomodulator was tested in cockerel chicks. Forty day old chicks were allocated into two groups A and B. Group A received Levamisole at the recommended dosage of 10.05mg/20 birds for 3 days prior to the NDV vaccinations (B1, LaSota and Komarov). Group B received all the afore mentioned vaccinations but was not treated with Levamisole. Sera ...

Inactivated Mycobacterium phlei inhalation ameliorates allergic asthma through modulating the balance of CD4+CD25+ regulatory T and Th17 cells in mice

Objective(s): Th2 response is related to the aetiology of asthma, but the underlying mechanism is unclear. To address this point, the effect of nebulized inhalation of inactivated Mycobacterium phlei on modulation of asthmatic  airway  inflammation was investigated. Materials and Methods: 24 male BALB/c mice were randomly divided into three groups: control group (Group A), asthma model group (G...

Effect of In Ovo Injection of VG/GA Vaccine, an Apathogenic Enteric Strain of Newcastle Disease Vaccine and Aluminum Hydroxide as an Adjuvant on Hatchability and Immune Response of Commercial Pullets

Current vaccination strategies for commercial poultry using live attenuated and inactivated Newcastle disease (ND) vaccines have some limitation and difficulties, and new vaccines with distinct features are needed. Recently, in ovo vaccination technology is concerned as a safe, efficacious, and convenient method. Common ND vaccines used in chickens cannot be employed in ovo due to embryo toxici...

Inhaled inactivated-Mycobacterium phlei modulates γδT cell function and alleviates airway inflammation in a mouse model of asthma.

BACKGROUND Mycobacterium bovis Bacille Calmette-Guérin (BCG) and other mycobacterial infections suppress airway hyperresponsiveness and eosinophilic inflammation in asthma.γδT cells are important modulators of airway function and allergic inflammation. Vγ1+γδT cells increase eosinophilic airway inflammation and airway hyperresponsiveness, while Vγ4+γδT reduce airway hyperresponsiveness. The obj...

Development and Manufacture of an Inactive Oil Emulsion Newcastle Disease Vaccine in Iran